Description

Ethyl Hydrogen trans-Cyclohexane-1,2-Dicarboxylate is a high-purity, versatile diester derivative of cyclohexane-1,2-dicarboxylic acid. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and functional group compatibility. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing cardiovascular and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its stereochemistry can influence biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as hydrogenation and cross-coupling reactions.
• Polymer Modification: Employed as a monomer or cross-linking agent to introduce cycloaliphatic structures into polyesters and coatings, enhancing durability and chemical resistance.
• Flavor and Fragrance Industry: Intermediate for the synthesis of complex ester-based aroma chemicals.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	Ethyl Hydrogen trans-Cyclohexane-1,2-Dicarboxylate
CAS No.	97718-55-3
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	trans-1,2-Cyclohexanedicarboxylic Acid Monoethyl Ester; Ethyl Hydrogen trans-1,2-Cyclohexanedicarboxylate; Monoethyl trans-Cyclohexane-1,2-dicarboxylate; trans-Cyclohexane-1,2-dicarboxylic Acid Monoethyl Ester; Ethyl (1R,2R)-1,2-Cyclohexanedicarboxylate (for enantiomer); Ethyl (1S,2S)-1,2-Cyclohexanedicarboxylate (for enantiomer); 1-Carboxy-2-ethoxycarbonylcyclohexane (trans-); (1R,2R)-Cyclohexane-1,2-dicarboxylic Acid Monoethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl Hydrogen trans-Cyclohexane-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.