Description

1-Bicyclo[2.2.1]Hept-5-En-2-Yl-4-Hydroxybutan-2-One is a specialized organic compound featuring a norbornene core linked to a hydroxybutanone functional group, making it a valuable chiral building block and synthetic intermediate. This compound matters for its ability to introduce structural complexity and specific stereochemistry into target molecules, which is critical for developing advanced materials and active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in asymmetric synthesis and polymer science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, particularly those requiring the rigid norbornene scaffold.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where its unique bicyclic structure can contribute to biological activity.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development and screening of new asymmetric catalytic systems.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic & Industrial Research: A valuable tool for methodological studies in organic synthesis, including cycloaddition reactions and functional group transformations.

Basic Information

Product Name	1-Bicyclo[2.2.1]Hept-5-En-2-Yl-4-Hydroxybutan-2-One
CAS No.	97403-92-4
Molecular Formula	C₁₁H₁₆O₂
Molecular Weight	180.24 g/mol
Synonyms	4-Hydroxy-1-(5-norbornen-2-yl)-2-butanone; 5-Norbornene-2-ethanol, β-acetyl-; 2-Butanone, 1-(5-norbornen-2-yl)-4-hydroxy-; 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-4-hydroxybutan-2-one; Norbornene hydroxybutanone; 5-Norbornene-2-ethanol, β-acetyl- (8CI); 1-(5-Norbornen-2-yl)-4-hydroxy-2-butanone
EINECS	Contact for details

Quality Control

Our 1-Bicyclo[2.2.1]Hept-5-En-2-Yl-4-Hydroxybutan-2-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), chiral purity, and impurity profiles are available upon request. We adhere to cGMP principles for pharmaceutical-grade material and can support custom purity requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.