Description

4-Nitroacetophenone is a versatile and important organic intermediate characterized by its nitro-substituted aromatic ketone structure. This compound is valued for its reactivity, serving as a key building block in the synthesis of more complex molecules across several high-value industries. It is primarily sought after by manufacturers and R&D teams in the pharmaceutical, agrochemical, and fine chemical sectors for its role in creating active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing amine or heterocyclic functionalities.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, pesticides, and plant growth regulators where its nitro group is a key reactive site.
• Dye and Pigment Production: Serves as an intermediate for creating azo dyes and other complex colorants.
• Organic Synthesis & Research: A valuable reagent in academic and industrial laboratories for constructing complex organic molecules, including chalcones and other fine chemicals.
• Photographic Chemical: Can be utilized in the synthesis of certain light-sensitive compounds.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions for carbon-carbon bond formation.

Basic Information

Product Name	4-Nitroacetophenone
CAS No.	100-19-6
Molecular Formula	C8H7NO3
Molecular Weight	165.15 g/mol
Synonyms	p-Nitroacetophenone; 1-(4-Nitrophenyl)ethanone; 4'-Nitroacetophenone; Methyl 4-nitrophenyl ketone; p-Nitrophenyl methyl ketone; 4-Nitroacetylbenzene; NSC 6648; 4-NAP
EINECS	202-826-9

Quality Control

Our 4-Nitroacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.