Description

(E)-3-(4'-Bromo[1,1'-Biphenyl]-4-Yl)-3-(4-Chlorophenyl)-N,n-Dimethylallylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex biphenyl structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors need this precise chemical to drive innovation in drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Heck) to construct complex polyaromatic systems for material science applications.
• Agrochemical Research: Serves as a key synthon in developing new generation pesticides and herbicides with specific activity profiles.
• Ligand and Catalyst Development: The biphenyl-chlorophenyl core can be utilized to develop novel chiral ligands for asymmetric catalysis.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in medicinal and synthetic organic chemistry.
• Scale-up & Process Chemistry: Supports process development and optimization for the commercial-scale production of target molecules.

Basic Information

Product Name	(E)-3-(4'-Bromo[1,1'-Biphenyl]-4-Yl)-3-(4-Chlorophenyl)-N,n-Dimethylallylamine Hydrochloride
CAS No.	97392-66-0
Molecular Formula	C23H21BrClN • HCl
Molecular Weight	464.79 g/mol (Free base: 428.78 g/mol)
Synonyms	(E)-3-(4'-Bromo-[1,1'-biphenyl]-4-yl)-3-(4-chlorophenyl)-N,N-dimethylprop-2-en-1-amine hydrochloride; N,N-Dimethyl-1-[4'-(4-bromophenyl)-4-chlorobiphenyl-3-yl]-2-propen-1-amine hydrochloride; (E)-3-(4'-Bromobiphenyl-4-yl)-3-(4-chlorophenyl)-N,N-dimethylallylamine HCl; 4'-Bromo-4-chloro-α-(dimethylaminomethyl)stilbene hydrochloride; Allylamine, 3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-(4-chlorophenyl)-N,N-dimethyl-, hydrochloride, (E)-; 97392-66-0 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our (E)-3-(4'-Bromo[1,1'-Biphenyl]-4-Yl)-3-(4-Chlorophenyl)-N,n-Dimethylallylamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques (HPLC, NMR, MS). We support compliance with ICH guidelines for impurities and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.