Description

trans-2-Methylcyclopropanamine Hydrochloride is a high-purity, chiral cyclopropylamine derivative in its stable hydrochloride salt form. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is essential for research and production in pharmaceutical chemistry, agrochemical development, and materials science, where its rigid cyclopropane ring structure imparts unique conformational and steric properties to target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of proprietary drug candidates, including potential central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or a reactive handle in probe molecules for studying enzyme mechanisms and protein interactions.
• Material Science Precursor: Utilized in the synthesis of specialized polymers and advanced organic materials with tailored properties.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratory settings.

Basic Information

Product Name	trans-2-Methylcyclopropanamine Hydrochloride
CAS No.	97291-62-8
Molecular Formula	C4H9N·HCl
Molecular Weight	107.58 g/mol (Free base: 71.12 g/mol)
Synonyms	(1R,2S)-2-Methylcyclopropanamine Hydrochloride; (1S,2R)-2-Methylcyclopropanamine Hydrochloride; trans-2-Methylcyclopropylamine HCl; trans-2-Aminomethylcyclopropane Hydrochloride; 2-Methylcyclopropanamine Hydrochloride (trans-); rel-(1R,2S)-2-Methylcyclopropanamine Hydrochloride; Cyclopropanamine, 2-methyl-, hydrochloride, trans-; (±)-trans-2-Methylcyclopropanamine Hydrochloride
EINECS	Contact for details

Quality Control

Our trans-2-Methylcyclopropanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and cGMP manufacturing. A Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans- isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.