Description

N(Alpha)-(Diphenoxyphosphoryl)Alanylproline is a specialized organophosphorus compound featuring a unique peptide-like backbone. This chemical is significant as a high-value synthetic intermediate and a potential building block for advanced research in medicinal chemistry and biochemistry. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and academic institutions focused on developing novel enzyme inhibitors or prodrugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex peptide mimetics and protease inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases and peptidases.
• Agrochemical Development: Acts as a specialized intermediate in the design of novel, targeted pesticides and herbicides.
• Chemical Biology Probes: Employed in the development of activity-based probes for studying protein function and interaction.
• Academic & Contract Research: Utilized in university and CRO settings for method development and novel synthetic route exploration.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-purity organic compounds.

Basic Information

Product Name	N(Alpha)-(Diphenoxyphosphoryl)Alanylproline
CAS No.	97280-40-5
Molecular Formula	C21H23N2O6P
Molecular Weight	430.39 g/mol
Synonyms	N(α)-(Diphenoxyphosphoryl)-L-alanyl-L-proline; (S)-1-((S)-2-((Diphenoxyphosphoryl)amino)propanoyl)pyrrolidine-2-carboxylic Acid; Diphenoxyphosphoryl-Ala-Pro-OH; Ala-Pro Diphenyl Phosphoramidate; N-(Diphenoxyphosphinyl)alanylproline; L-Alanyl-L-proline, N-[ (diphenoxyphosphinyl)oxy]-; Proline, N-[N-[ (diphenoxyphosphinyl)-L-alanyl]-]
EINECS	Contact for details

Quality Control

Our N(Alpha)-(Diphenoxyphosphoryl)Alanylproline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.