Description

(Z)-2-Methoxyimino-2-(Furyl-2-Yl) Acetic Acid Ammonium Salt is a high-purity, synthetic organic salt with significant utility as a key pharmaceutical intermediate. Its value lies in its role as a critical building block for the synthesis of advanced cephalosporin antibiotics, ensuring the structural integrity and efficacy of the final active pharmaceutical ingredient (API). This compound is essential for manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality raw materials for antibiotic production under stringent Good Manufacturing Practice (GMP) standards.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of third and fourth-generation cephalosporin antibiotics, such as cefuroxime axetil.
• API Synthesis: Used in the final chemical steps to construct the β-lactam core structure of advanced antibiotics.
• Fine Chemical Production: Serves as a specialized building block for research and development of novel antimicrobial agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP-compliant drug substance manufacturing.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships in β-lactam chemistry.

Basic Information

Product Name	(Z)-2-Methoxyimino-2-(Furyl-2-Yl) Acetic Acid Ammonium Salt
CAS No.	97148-39-5
Molecular Formula	C8H10N2O4
Molecular Weight	198.18 g/mol
Synonyms	(Z)-2-(2-Furyl)-2-(Methoxyimino)acetic Acid Ammonium Salt; Ammonium (Z)-2-(2-Furyl)-2-(methoxyimino)acetate; (Z)-Syn Isomer of Methoxyimino Furyl Acetic Acid Ammonium Salt; Cefuroxime Axetil Intermediate; (Z)-MOFA Ammonium Salt; (2Z)-2-(2-Furanyl)-2-[(Methyloxy)imino]ethanoic Acid Ammonium Salt; Ammonium (Z)-α-(Methoxyimino)-2-furanacetate
EINECS	Contact for details

Quality Control

Our (Z)-2-Methoxyimino-2-(Furyl-2-Yl) Acetic Acid Ammonium Salt is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, isomeric content, and impurity profiles. We can support development with specifications aligned with ICH guidelines and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Isomeric Purity (Z-Isomer, HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.