Description

1,4-Dioxa-Spiro[4.5]Dec-8-Ylamine is a versatile spirocyclic amine building block with the CAS number 97096-16-7. This compound is valued for its unique bicyclic structure, which incorporates both an amine functionality and a protected carbonyl equivalent, making it a critical intermediate in complex organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures, including active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring complex, three-dimensional spirocyclic frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can contribute to unique biological activity.
• Organic Synthesis Reagent: Serves as a versatile amine component in nucleophilic substitution reactions, reductive aminations, and as a precursor for heterocyclic compounds.
• Material Science Research: Potential monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Useful scaffold for creating molecular probes and tools due to its amine handle for bioconjugation.

Basic Information

Item	Details
Product Name	1,4-Dioxa-Spiro[4.5]Dec-8-Ylamine
CAS No.	97096-16-7
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	8-Amino-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decan-8-amine; 8-Amino-1,4-dioxaspiro[4.5]decane; Spirocyclic amine intermediate; 1,4-Dioxa-8-azaspiro[4.5]decane (tautomeric form); 8-Amino-1,4-dioxa-spiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-Spiro[4.5]Dec-8-Ylamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.