Description

4,7-Methano-1H-Indene-2-Carboxylic Acid, Octahydro-, (2α,3aβ,4α,7α,7aβ)- (9CI) is a complex, stereochemically defined bicyclic carboxylic acid derivative. This compound matters as a sophisticated chemical building block, offering a rigid, polycyclic framework that is valuable for advanced synthetic chemistry and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex molecular architectures.
• Agrochemical Synthesis: Used in the creation of novel, high-performance pesticides and herbicides where its unique carbon skeleton can contribute to specific biological activity and environmental stability.
• Advanced Material Research: Acts as a precursor or monomer in the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, non-planar structure.
• Catalyst & Ligand Development: Employed as a backbone for constructing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis, total synthesis of natural products, and stereochemistry investigations.
• Fine Chemical Production: Incorporated into the multi-step synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	4,7-Methano-1H-Indene-2-Carboxylic Acid, Octahydro-, (2α,3aβ,4α,7α,7aβ)- (9CI)
CAS No.	96844-71-2
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	(2α,3aβ,4α,7α,7aβ)-Octahydro-4,7-methano-1H-indene-2-carboxylic acid; Octahydro-4,7-methano-1H-indene-2-carboxylic acid, (2α,3aβ,4α,7α,7aβ)-; 4,7-Methano-1H-indole-2-carboxylic acid, octahydro-, (2-alpha,3a-beta,4-alpha,7-alpha,7a-beta)-; 1H-Indene-2-carboxylic acid, octahydro-4,7-methano-, (2α,3aβ,4α,7α,7aβ)-; Bicyclo[2.2.1]heptane-2-carboxylic acid derivative; endo,endo-Octahydro-4,7-methanoindene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR/IR for structural verification. We provide detailed Certificates of Analysis (COA) with all shipments, ensuring full traceability and compliance with your research or cGMP guidelines for early-phase development, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is compatible with strong acids and organic solvents but should be kept separate from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.