Description

1-Azaspiro[4.4]Nonane-2-Carboxylicacid(9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new therapeutic candidates with improved efficacy and selectivity profiles.

Application

• Pharmaceutical Intermediate: A key scaffold for the research and development of new drug candidates targeting neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained, three-dimensional geometry.
• Process Chemistry & Scale-Up: Serves as a starting material or advanced intermediate in the pilot and commercial-scale synthesis of complex molecules.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for derivatization, making it useful for creating chemical probes and bioconjugates for biological studies.
• Academic & Contract Research: Employed in university and CRO settings for exploratory synthetic chemistry and the discovery of new bioactive compounds.

Basic Information

Product Name	1-Azaspiro[4.4]Nonane-2-Carboxylicacid(9Ci)
CAS No.	96798-47-9
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-Azaspiro[4.4]nonane-2-carboxylic acid; 2-Carboxy-1-azaspiro[4.4]nonane; 1-Azaspiro[4.4]nonane-2-carboxylic acid (9CI); Azaspiro[4.4]nonane-2-carboxylic acid; Spirocyclic proline analog
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[4.4]Nonane-2-Carboxylicacid(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.