Description

4-(2'-n-Boc-Hydrazino)Benzoic Acid is a high-purity, protected hydrazine derivative of benzoic acid, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile, protected hydrazino handle for the controlled construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for peptide coupling, heterocycle synthesis, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptide Mimetic Synthesis: Used to incorporate hydrazino and hydrazide functionalities into peptide backbones, creating protease-resistant analogs.
• Heterocyclic Chemistry: Serves as a precursor for the construction of various nitrogen-containing heterocycles like pyrazoles, triazoles, and oxadiazoles.
• Bioconjugation & Linker Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other bioconjugates where a protected, reactive handle is required.
• Agrochemical Research: Intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.

Basic Information

Product Name	4-(2'-n-Boc-Hydrazino)Benzoic Acid
CAS No.	96736-00-4
Molecular Formula	C₁₃H₁₈N₂O₄
Molecular Weight	266.29 g/mol
Synonyms	4-[(2-{[(tert-Butoxy)carbonyl]amino}ethyl)amino]benzoic Acid; 4-(2-Boc-Hydrazino)Benzoic Acid; 4-(N-Boc-Hydrazino)Benzoic Acid; 4-(2-(tert-Butoxycarbonyl)hydrazinyl)benzoic Acid; Benzoic acid, 4-[(2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl)amino]-; 4-(2'-N-Boc-hydrazino)benzoic acid; tert-Butyl N-[2-(4-carboxyphenyl)hydrazinyl]carbamate; Boc-Hydrazino-PABA
EINECS	Contact for details

Quality Control

Our 4-(2'-n-Boc-Hydrazino)Benzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and cGMP manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support regulatory filings with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.