Description

2,5-Piperazinedicarboxylicacid,trans-(9Ci) is a high-purity, trans-configured piperazine derivative with significant utility in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of complex pharmaceutical molecules and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Ligand Synthesis: Used in the preparation of sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics: Serves as a constrained scaffold in the design of peptide mimics for drug discovery programs.
• Agrochemical Research: Employed as a building block for developing new crop protection agents with specific biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	2,5-Piperazinedicarboxylicacid,trans-(9Ci)
CAS No.	96705-92-9
Molecular Formula	C6H10N2O4
Molecular Weight	174.16 g/mol
Synonyms	(2R,5R)-Piperazine-2,5-dicarboxylic acid; trans-2,5-Piperazinedicarboxylic Acid; (R,R)-2,5-Dicarboxypiperazine; (2R,5R)-2,5-Piperazinedicarboxylic acid; (R,R)-Piperazine-2,5-dicarboxylic acid; (2R,5R)-Hexahydropyrazine-2,5-dicarboxylic acid; trans-Hexahydropyrazine-2,5-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedicarboxylicacid,trans-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality management system supports compliance with cGMP standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.