Description

1-Deoxy-1-Nitro-D-Iditol Hemihydrate is a specialized carbohydrate derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a valuable chiral intermediate and building block for the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of complex sugar-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those with carbohydrate or nucleoside-like structures.
• Medicinal Chemistry Research: Used as a building block for creating libraries of compounds for high-throughput screening against various biological targets.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex molecules in pilot plants and manufacturing settings.
• Glycochemistry & Glycobiology: Acts as a precursor or model compound in studies involving modified sugars, glycosidase inhibitors, or glycomimetics.
• Bioconjugation & Probe Development: Useful for synthesizing labeled sugars or conjugates for diagnostic or biochemical probing applications.
• Academic & Institutional Research: Serves as a reagent for methodological studies in synthetic organic chemistry and asymmetric synthesis at universities and government labs.

Basic Information

Product Name	1-Deoxy-1-Nitro-D-Iditol Hemihydrate
CAS No.	96613-89-7
Molecular Formula	C6H13NO7 • ½H2O
Molecular Weight	212.17 g/mol (Anhydrous basis)
Synonyms	1-Deoxy-1-nitro-D-iditol hemihydrate; 1-Deoxy-1-nitro-iditol (hemihydrate); D-Iditol, 1-deoxy-1-nitro-, hemihydrate; 1-Nitro-1-deoxy-D-iditol hemihydrate; Nitrodeoxyiditol hemihydrate; 96613-89-7 (CAS); 1-Deoxy-1-nitro-D-iditol (0.5 hydrate)
EINECS	Contact for details

Quality Control

Our 1-Deoxy-1-Nitro-D-Iditol Hemihydrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, chiral purity, and water content. We support custom synthesis and purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	3.5 - 5.5% (Theoretical for hemihydrate: ~4.2%)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.