Description

2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-14C is a carbon-14 labeled derivative of a heterocyclic aromatic amine, a critical tool for advanced research and analytical applications. This isotopically labeled compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies where tracking the molecule is required. It is primarily utilized by research scientists and analytical laboratories in the fields of toxicology, food safety, and environmental health to investigate the formation, distribution, and biological impact of related compounds.

Application

• Tracer Studies in Metabolism Research: Used as a radiolabeled tracer to study the absorption, distribution, metabolism, and excretion (ADME) of heterocyclic aromatic amines (HAAs) in biological systems.
• Analytical Method Development: Serves as an internal standard or reference material in the development and validation of highly sensitive analytical methods, such as LC-MS/MS, for the detection of HAAs.
• Food Chemistry and Safety: Employed in research to understand the formation mechanisms and quantify the levels of potentially carcinogenic HAAs in cooked protein-rich foods.
• Environmental Toxicology: Applied in studies assessing the environmental fate, bioaccumulation, and ecotoxicological effects of related aromatic amine contaminants.
• Biomarker Research: Utilized in the investigation of DNA adduct formation and other biochemical interactions to elucidate mechanisms of genotoxicity and carcinogenicity.
• Pharmaceutical Research: Acts as a specialized reagent in drug discovery programs targeting related molecular pathways or in safety pharmacology studies.

Basic Information

Product Name	2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-14C
CAS No.	96600-60-1
Molecular Formula	C11H914CN6 *
Molecular Weight	~214.22 g/mol (for unlabeled form)
Synonyms	2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-14C
MeIQx-2-14C
2-Amino-3,8-dimethyl-3H-imidazo[4,5-f]quinoxaline-2-14C
14C-Labeled MeIQx
2-14C-MeIQx
[2-14C]-2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline
Radiolabeled Heterocyclic Aromatic Amine
EINECS	Contact for details

* Note: Formula indicates carbon-14 label at the 2-position. Exact specific activity and radiochemical purity are provided on the Certificate of Analysis.

Quality Control

Every batch of our 2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-14C is produced and handled under strict quality protocols to ensure traceability and reliability for critical research. We provide comprehensive analytical data including radiochemical purity, specific activity, and chemical purity, typically determined by HPLC with radiometric and UV detection. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or as specified on the label). This product is hygroscopic (moisture-sensitive); ensure the container is sealed properly after each use to prevent degradation. For long-term storage of radioactive materials, follow all local and institutional regulations for handling and containment.

Specification

Item	Specification
Appearance	Solid (Color to be specified on COA)
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 95%
Specific Activity	Customizable (mCi/mmol)
Solvent (if supplied as solution)	Specified on COA
Concentration (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.