Description

3-Amino-6-Bromoquinazolin-4(3H)-One is a high-value brominated quinazolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure makes it a versatile building block for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tyrosine kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Building block for developing novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probe: Used in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Material Science: Intermediate for creating functionalized organic molecules with potential electronic or photophysical properties.
• Academic & Contract Research: Essential reagent for methodological development in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	3-Amino-6-Bromoquinazolin-4(3H)-One
CAS No.	96498-79-2
Molecular Formula	C8H6BrN3O
Molecular Weight	240.06 g/mol
Synonyms	6-Bromo-3-amino-4(3H)-quinazolinone; 3-Amino-6-bromo-4(3H)-quinazolinone; 6-Bromo-3-aminoquinazolin-4-one; 4(3H)-Quinazolinone, 3-amino-6-bromo-; 96498-79-2; 3-Amino-6-bromoquinazolin-4-ol; 6-Bromo-3-amino-4-hydroxyquinazoline
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Bromoquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements of research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.