Description

n-Cbz-Isoindoline-1-Carboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing isoindoline or related heterocyclic scaffolds.
• Peptide Mimetics & PROTACs: Used in the design and synthesis of peptide-like molecules and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Medicinal Chemistry Research: Employed as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.
• Chemical Biology Probes: Utilized in the development of chemical probes and tools for studying biological pathways and enzyme functions.

Basic Information

Product Name	n-Cbz-Isoindoline-1-Carboxylic Acid
CAS No.	96325-10-9
Molecular Formula	C17H15NO4
Molecular Weight	297.31 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]isoindoline-1-carboxylic acid; 1-Carboxy-1-isoindolinecarboxylic acid benzyl ester; 1-Cbz-isoindoline-1-carboxylic acid; N-Carbobenzyloxy-isoindoline-1-carboxylic Acid; 1-(Benzyloxycarbonyl)isoindoline-1-carboxylic Acid; Z-Isoindoline-1-COOH; 1-(Cbz)-Isoindoline-1-Carboxylic Acid
EINECS	Contact for details

Quality Control

Our n-Cbz-Isoindoline-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.