Description

8-Ethynyl-1,4-Dioxaspiro[4.5]Decane CAS NO 96184-86-0 is a high-value, functionalized spirocyclic compound featuring a reactive ethynyl group. This unique structure makes it a versatile and critical building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Material Science Research: Serves as a precursor for novel polymers, ligands, and functional materials with tailored properties.
• Click Chemistry: The ethynyl group enables efficient Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and polymer functionalization.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.
• Ligand and Catalyst Development: Used to create sophisticated chelating agents and organometallic catalysts.

Basic Information

Item	Detail
Product Name	8-Ethynyl-1,4-Dioxaspiro[4.5]Decane
CAS No.	96184-86-0
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	8-Ethynyl-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-8-ethyne; 8-Ethynyl-1,4-dioxaspiro[4.5]dec-8-ene (common misnomer); Ethynyl-substituted spiroketal; Acetylene-spiroketal; Spiro[1,3-dioxolane-2,1'-cyclohexane]-4'-ethyne; 4'-Ethynylspiro[1,3-dioxolane-2,1'-cyclohexane]
EINECS	Contact for details

Quality Control

Our 8-Ethynyl-1,4-Dioxaspiro[4.5]Decane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.