Description

Ethyl 3-Exo-Aminobicyclo[2.2.1]Heptane-2-Exo-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant chiral building block and intermediate. This compound is valued for its rigid, three-dimensional bicyclic structure, which is crucial for imparting specific conformational properties in advanced drug molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, antiviral drugs, and other therapeutic candidates requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs).
• Neurological Drug Development: Used as a precursor in the creation of ligands and candidates targeting neurotransmitter receptors.
• Antiviral Research: Serves as a structural component in the design of protease inhibitors and other antiviral compounds.
• Asymmetric Synthesis: Employed as a building block in stereoselective chemical reactions to create complex molecules.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Biology: Acts as a probe or scaffold for studying enzyme interactions and biological pathways.

Basic Information

Product Name	Ethyl 3-Exo-Aminobicyclo[2.2.1]Heptane-2-Exo-Carboxylate Hydrochloride
CAS No.	95630-75-4
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	Ethyl 3-exo-aminobicyclo[2.2.1]heptane-2-exo-carboxylate HCl; 2-exo-Carbethoxy-3-exo-aminonorbornane hydrochloride; 3-exo-Amino-2-exo-ethoxycarbonylbicyclo[2.2.1]heptane hydrochloride; Ethyl 3-endo-amino-2-endo-carboxylate bicyclo[2.2.1]heptane hydrochloride (related isomer); exo,exo-2-Carbethoxy-3-aminonorbornane hydrochloride; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, ethyl ester, hydrochloride, (2-exo,3-exo)-; 95630-75-4; Aminonorbornane carboxylate ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 3-Exo-Aminobicyclo[2.2.1]Heptane-2-Exo-Carboxylate Hydrochloride is manufactured under strict quality systems suitable for pharmaceutical research. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting standards. Comprehensive Certificates of Analysis (COA) documenting identity, assay, impurity profile, and residual solvents are provided to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.