Description

(S)-2-(Methoxymethyl)Pyrrolidine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its well-defined stereochemistry, which is crucial for imparting specific biological activity in final target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of various drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: Employed in chemical research for method development and the synthesis of complex natural products or novel molecular architectures.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring a specific (S)-configured pyrrolidine moiety.

Basic Information

Product Name	(S)-2-(Methoxymethyl)Pyrrolidine Hydrochloride
CAS No.	95312-81-5
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	(S)-(-)-2-(Methoxymethyl)pyrrolidine hydrochloride; (S)-2-(Methoxymethyl)-1-azacyclopentane hydrochloride; L-Prolinol, O-methyl-, hydrochloride, (S)-; (S)-(-)-2-Methoxymethylpyrrolidine HCl; (S)-N-Methyl-2-pyrrolidinemethanol hydrochloride (incorrect but common search); (2S)-2-(Methoxymethyl)pyrrolidine hydrochloride; (S)-α-(Methoxymethyl)-pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-(Methoxymethyl)Pyrrolidine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.