Description

2-Methyl-8-Trifluoromethyl-Quinoline is a specialized fluorinated quinoline derivative, a high-value building block prized for its unique electronic and steric properties imparted by the trifluoromethyl group. This compound is essential for advanced research and development in medicinal chemistry and materials science, where its structure serves as a key scaffold. It is primarily sought by pharmaceutical researchers for drug discovery programs and by agrochemical developers for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a precursor for developing advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport materials.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis, benefiting from the electron-withdrawing nature of the trifluoromethyl group.
• Fluorescent Probe and Dye Chemistry: Acts as a core structure for synthesizing specialized fluorescent markers and dyes used in biochemical assays and imaging.

Basic Information

Product Name	2-Methyl-8-Trifluoromethyl-Quinoline
CAS No.	95256-55-6
Molecular Formula	C11H8F3N
Molecular Weight	211.18 g/mol
Synonyms	8-(Trifluoromethyl)-2-methylquinoline; 2-Methyl-8-(trifluoromethyl)quinoline; Quinoline, 2-methyl-8-(trifluoromethyl)-; 2-Methyl-8-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 2-Methyl-8-Trifluoromethyl-Quinoline is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom purity requirements for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.