Description

Pyrimidine Pathway Regulator 1 (CAS No. 95077-80-8) is a specialized organic compound designed to modulate key enzymatic steps within the pyrimidine biosynthesis pathway. This targeted regulation is critical for controlling nucleotide precursor levels in biological systems, impacting cellular proliferation and metabolic function. It is an essential research-grade biochemical for pharmaceutical development, agricultural science, and advanced life science research, where precise control of nucleotide metabolism is required.

Application

• Pharmaceutical Research & Development: As a key biochemical tool for studying and targeting nucleotide metabolism in oncology, virology, and parasitology drug discovery programs.
• Enzymology Studies: Used as a specific inhibitor or modulator for enzymes like dihydroorotate dehydrogenase (DHODH) within the de novo pyrimidine synthesis pathway.
• Agricultural Chemical Development: Serves as a lead compound or intermediate in the synthesis of novel fungicides or herbicides that disrupt pathogen or weed growth.
• Cell Culture & Metabolic Research: Employed to manipulate intracellular pyrimidine nucleotide pools to study cell cycle progression, differentiation, and immune cell function.
• Biochemical Standard: Used as a high-purity reference standard for analytical method development and quality control in related API manufacturing.

Basic Information

Item	Detail
Product Name	Pyrimidine Pathway Regulator 1
CAS No.	95077-80-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Brequinar; Brequinar Sodium; DUP-785; NSC 339768; 6-Fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid; 6-Fluoro-2-(2-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid; Pyrimidine Synthesis Inhibitor
EINECS	Contact for details

Quality Control

Our Pyrimidine Pathway Regulator 1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.