Description

3-Deoxyoctulosonic Acid-(α-2-4)-3-Deoxyoctulosonic Acid is a specialized disaccharide derivative of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo), a key component of bacterial lipopolysaccharides. This compound is critical for research into the structure, biosynthesis, and immunogenicity of Gram-negative bacterial cell walls. It serves as a valuable reference standard and synthetic intermediate for scientists in pharmaceutical development, glycobiology, and immunology, enabling the study of host-pathogen interactions and the design of novel therapeutics and vaccines.

Application

• Glycobiology Research: Used as a precise biochemical tool for studying the assembly and function of bacterial lipopolysaccharide (LPS) and its role in pathogenesis.
• Immunology & Vaccine Development: Serves as a defined antigenic structure for investigating immune responses to bacterial infections and for the rational design of conjugate vaccines.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for the identification and quantification of Kdo-containing glycans in complex biological samples.
• Enzymology Studies: Acts as a substrate or inhibitor for enzymes involved in LPS biosynthesis, such as Kdo transferases, to elucidate catalytic mechanisms and screen for potential inhibitors.
• Synthetic Chemistry Intermediate: Provides a crucial building block for the chemical and chemoenzymatic synthesis of more complex oligosaccharides and glycoconjugates mimicking bacterial cell wall structures.
• Microbiology & Diagnostics: Utilized in the development of specific detection assays and biosensors for Gram-negative bacterial contaminants or pathogens.

Basic Information

Product Name	3-Deoxyoctulosonic Acid-(α-2-4)-3-Deoxyoctulosonic Acid
CAS No.	94722-74-4
Molecular Formula	C16H24O17
Molecular Weight	488.36 g/mol
Synonyms	Kdo-(α2-4)-Kdo; 3-Deoxy-D-manno-oct-2-ulosonic acid-(2→4)-3-deoxy-D-manno-oct-2-ulosonic acid; Kdo disaccharide; α-Kdo-(2→4)-α-Kdo; 3-Deoxy-D-manno-octulosonic acid dimer; Lipopolysaccharide core disaccharide; Bacterial Kdo disaccharide; 3-Deoxyoctulosonyl-(2→4)-3-deoxyoctulosonate
EINECS	Contact for details

Quality Control

Every batch of our 3-Deoxyoctulosonic Acid-(α-2-4)-3-Deoxyoctulosonic Acid is produced and analyzed under strict quality management protocols. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) providing full characterization data is supplied with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.