Description

α-Amino-α-Methyl-β-Carboxyethanephosphinic Acid is a specialized organophosphorus compound featuring a unique phosphinic acid backbone integrated with amino and carboxylic acid functional groups. This molecular architecture makes it a valuable intermediate for synthesizing novel bioactive molecules and advanced materials. It is particularly sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating targeted enzyme inhibitors and chelating agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting metabolic enzymes or requiring metal chelation.
• Agrochemical Research: Used in developing advanced herbicides, plant growth regulators, or fungicides with specific modes of action.
• Biochemical Probe Development: Serves as a precursor for creating selective enzyme inhibitors used in biochemical and pharmacological research.
• Coordination Chemistry & Chelation: Acts as a versatile ligand for metal ions in catalytic systems or for analytical separation purposes.
• Material Science Precursor: Potential intermediate in the synthesis of flame-retardant additives or specialty polymers with specific functional properties.
• Peptidomimetic Chemistry: Incorporated into peptide analogs to enhance stability, bioavailability, or to introduce phosphonate-based bioisosteres.

Basic Information

Product Name	α-Amino-α-Methyl-β-Carboxyethanephosphinic Acid
CAS No.	94650-45-0
Molecular Formula	C5H10NO5P
Molecular Weight	195.11 g/mol
Synonyms	2-Amino-2-methyl-3-carboxypropylphosphinic acid; (2-Amino-2-methyl-3-carboxypropyl)phosphinic acid; 3-Carboxy-2-methyl-2-aminopropylphosphinic acid; AMPA analog (phosphinic); NSC 339586; Phosphinothricin precursor; α-Amino-α-methyl-β-carboxyethanephosphonate
EINECS	Contact for details

Quality Control

Our α-Amino-α-Methyl-β-Carboxyethanephosphinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place (recommended 15-25°C) under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.