Description

12-Hydroxymethylbenzo(A)Pyrene is a high-purity, functionalized derivative of benzo[a]pyrene, a polycyclic aromatic hydrocarbon (PAH). This compound is of significant value as a key synthetic intermediate and a critical reference standard in advanced chemical research and development. It is primarily utilized by research institutions, analytical laboratories, and specialty chemical manufacturers engaged in environmental monitoring, toxicology studies, and the synthesis of complex organic molecules. Our supply is characterized by stringent quality control to ensure reliability for sensitive applications.

Application

• Chemical Reference Standard: Used as a certified analytical standard for the calibration of equipment and validation of methods in environmental and food safety testing for PAH contamination.
• Metabolite Research: Serves as a crucial intermediate or metabolite analog in biochemical and toxicological studies investigating the metabolic pathways and carcinogenic mechanisms of benzo[a]pyrene.
• Organic Synthesis: Acts as a versatile building block for the synthesis of more complex, functionalized PAH derivatives for material science or pharmaceutical research.
• Environmental Analysis: Employed in method development and quality control for the detection and quantification of hydroxylated PAH metabolites in complex matrices like soil, water, and biological samples.
• Biomarker Studies: Utilized in the development of immunoassays or other diagnostic tools aimed at detecting specific PAH-DNA adducts or metabolites as exposure biomarkers.

Basic Information

Product Name	12-Hydroxymethylbenzo(A)Pyrene
CAS No.	94500-43-3
Molecular Formula	C₂₁H₁₄O
Molecular Weight	282.34 g/mol
Synonyms	12-(Hydroxymethyl)benzo[a]pyrene; 12-Hydroxymethylbenzo[a]pyrene; 12-HMBP; Benzo[a]pyren-12-ylmethanol; 12-Methylolbenzo[a]pyrene; 12-Hydroxymethyl-BaP; BaP-12-CH₂OH
EINECS	Contact for details

Quality Control

Every batch of 12-Hydroxymethylbenzo(A)Pyrene is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep the container sealed to prevent contamination and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in common organic solvents (e.g., DMSO, methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.