Description

(25R)-7α-[[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl]Oxy]-26-Hydroxycholest-4-En-3-One is a high-purity, semi-synthetic steroidal glycoside of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules targeting metabolic and endocrine pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex steroidal drugs and prodrugs.
• Reference Standard: Used in analytical method development and validation for quality control (QC) and regulatory submissions.
• Biochemical Research: Tool compound for investigating steroid hormone biosynthesis, metabolism, and receptor interactions.
• Metabolic Pathway Studies: Probe for studying enzymes like cytochrome P450s and hydroxysteroid dehydrogenases.
• Academic Research: Serves as a substrate or inhibitor in mechanistic studies within university and institutional labs.
• Process Development: Used in scaling up synthetic routes for new chemical entities (NCEs) in pilot plants.

Basic Information

Product Name	(25R)-7α-[[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl]Oxy]-26-Hydroxycholest-4-En-3-One
CAS No.	94426-00-3
Molecular Formula	C35H59NO8
Molecular Weight	621.85 g/mol
Synonyms	7α-(2-Acetamido-2-deoxy-β-D-glucopyranosyloxy)-26-hydroxycholest-4-en-3-one; 26-Hydroxy-7α-[(2-acetamido-2-deoxy-β-D-glucopyranosyl)oxy]cholest-4-en-3-one; (25R)-26-Hydroxycholest-4-en-3-one 7α-(2-acetamido-2-deoxy-β-D-glucoside); Steroidal N-Acetylglucosaminide; A steroidal glycoside intermediate
EINECS	Contact for details

Quality Control

Our (25R)-7α-[[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl]Oxy]-26-Hydroxycholest-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.