Description

(R)-(-)-2-Chloro 3-Phenylpropionic Acid is a high-purity chiral building block of significant importance in asymmetric synthesis. This optically active compound serves as a critical intermediate for the development of enantiomerically pure pharmaceuticals and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Fine Chemical and Flavor/Fragrance Industry: Employed in the synthesis of complex, optically active molecules for specialty chemicals, flavors, and fragrances.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new synthetic routes to chiral compounds.

Basic Information

Product Name	(R)-(-)-2-Chloro 3-Phenylpropionic Acid
CAS No.	94347-44-1
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	(R)-2-Chloro-3-phenylpropanoic Acid; (R)-(-)-2-Chloro-3-phenylpropionic Acid; (R)-2-Chloro-3-phenylpropionic Acid; (R)-α-Chloro-β-phenylpropionic Acid; (2R)-2-Chloro-3-phenylpropanoic Acid; (R)-2-Chlorohydrocinnamic Acid; (R)-O-Chlorohydrocinnamic Acid; (R)-3-Phenyl-2-chloropropionic Acid
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Chloro 3-Phenylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for optical purity and chemical identity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess (ee), and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (ee)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.