Description

(2S,4S)-(+)-4-Bromomethyl-2-Phenyl-1,3-Dioxane is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and reactive bromomethyl group make it a crucial precursor for constructing complex, optically active molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, stereochemically defined intermediates for asymmetric synthesis and API development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific (2S,4S) stereochemistry.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of novel chiral ligands for asymmetric catalysis.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and insecticides.
• Fine Chemical and Specialty Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the development of new synthetic routes.
• Material Science Research: Potential precursor for chiral monomers in polymer chemistry and advanced functional materials.

Basic Information

Item	Details
Product Name	(2S,4S)-(+)-4-Bromomethyl-2-Phenyl-1,3-Dioxane
CAS No.	94340-00-8
Molecular Formula	C11H13BrO2
Molecular Weight	257.12 g/mol
Synonyms	(+)-(2S,4S)-4-(Bromomethyl)-2-phenyl-1,3-dioxane; (2S,4S)-4-Bromomethyl-2-phenyl-1,3-dioxolane (common misnomer); 4-Bromomethyl-2-phenyl-1,3-dioxane, (2S,4S)-(+)-; (S,S)-4-Bromomethyl-2-phenyl-1,3-dioxane; 2-Phenyl-4-bromomethyl-1,3-dioxane, (2S,4S)-form; Chiral 4-bromomethyl dioxane derivative
EINECS	Contact for details

Quality Control

Our (2S,4S)-(+)-4-Bromomethyl-2-Phenyl-1,3-Dioxane is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral GC), identity confirmation (IR, NMR), and assay determination. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% de (diastereomeric excess)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.