Description

3,3-[(2,2-Dimethylpropane-1,3-Diyl)Bis(Oxy)]-17Alpha-Hydroxyestr-5(10)-Ene-17-Carbonitrile is a high-purity steroidal nitrile derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its specific molecular architecture, which is engineered for targeted synthesis in the development of novel therapeutic agents. This compound is essential for research institutions and pharmaceutical manufacturers focused on steroid-based drug discovery and the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Drug Discovery & Research: Used in medicinal chemistry for the research and development of new therapeutic compounds targeting hormonal pathways.
• Steroid Derivative Synthesis: Serves as a precursor for creating modified steroid molecules with specific biological activities.
• Biochemical Research: Employed in academic and industrial laboratories for studying steroid-receptor interactions and metabolic pathways.
• Process Development: Utilized in scaling up and optimizing synthetic routes for commercial pharmaceutical manufacturing.

Basic Information

Product Name	3,3-[(2,2-Dimethylpropane-1,3-Diyl)Bis(Oxy)]-17Alpha-Hydroxyestr-5(10)-Ene-17-Carbonitrile
CAS No.	94291-97-1
Molecular Formula	C27H39NO3
Molecular Weight	425.61 g/mol
Synonyms	17α-Hydroxy-3,3-[(2,2-dimethyl-1,3-propanediyl)bis(oxy)]estr-5(10)-en-17-carbonitrile; 3,3-[(2,2-Dimethyltrimethylene)dioxy]-17α-hydroxyestr-5(10)-ene-17-carbonitrile; Estr-5(10)-ene-17-carbonitrile, 3,3-[(2,2-dimethyl-1,3-propanediyl)bis(oxy)]-17α-hydroxy-; Steroidal Nitrile Intermediate 94291-97-1; 17α-Cyano-3,3-(2,2-dimethylpropylenedioxy)estr-5(10)-en-17β-ol (tautomeric form); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,3-[(2,2-Dimethylpropane-1,3-Diyl)Bis(Oxy)]-17Alpha-Hydroxyestr-5(10)-Ene-17-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); handle and store under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.