Description

(9S)-9-Hydroxy-6'-Methoxycinchonanium Thiocyanate is a high-purity, chiral cinchona alkaloid derivative, specifically engineered for advanced chemical synthesis and analytical applications. This compound is valued for its role as a versatile chiral selector and phase-transfer catalyst, enabling precise stereochemical control in the production of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries where enantioselective synthesis and separation are critical.

Application

• As a chiral phase-transfer catalyst (PTC) in the asymmetric synthesis of pharmaceutical intermediates.
• As a chiral selector in the development and manufacturing of high-performance liquid chromatography (HPLC) columns for enantiomer separation.
• In the research and scale-up of enantioselective reactions, including alkylations, Michael additions, and epoxidations.
• For the synthesis of complex natural products and non-racemic chiral compounds in fine chemical production.
• As a key intermediate or reagent in the preparation of other functionalized cinchona alkaloid derivatives with tailored properties.
• In analytical method development as a reference standard for quality control in chiral chemistry.

Basic Information

Product Name	(9S)-9-Hydroxy-6'-Methoxycinchonanium Thiocyanate
CAS No.	94248-97-2
Molecular Formula	C₂₁H₂₅N₃O₂S
Molecular Weight	383.51 g/mol
Synonyms	(9S)-9-Hydroxy-6'-methoxycinchonan-9-ium thiocyanate; 9-Hydroxy-6'-methoxycinchonanium thiocyanate; Cinchonan-9-ol, 6'-methoxy-, (9S)-, thiocyanate (1:1); (9S)-6'-Methoxycinchonan-9-ol thiocyanate; Cinchona Alkaloid Derivative; Chiral Cinchona Ammonium Salt; PTC Catalyst from Cinchona; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (9S)-9-Hydroxy-6'-Methoxycinchonanium Thiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.