Description

[3Ar-[3Aalpha,4Alpha(S*),5Beta,6Aalpha]]-4-[2-Bromo-5-Cyclohexyl-5-Oxo-3-[(Trimethylsilyl)Oxy]-1-Pentenyl]Hexahydro-2H-Cyclopenta[B]-5-Furyl Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, multi-functional molecular structure. This compound is of significant value for research and development in synthetic organic chemistry, particularly for constructing intricate molecular frameworks. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and novel therapeutic agents.
• Organic Synthesis Research: Used in academic and industrial R&D for methodology development, exploring new carbon-carbon bond forming reactions, and studying stereoselective transformations.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Provides a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical manufacturing.
• Synthesis of Prostaglandin Analogues: The structural motifs suggest potential utility in the synthesis of prostaglandin or prostacyclin analogues, which are important in medicinal chemistry.

Basic Information

Item	Detail
Product Name	[3Ar-[3Aalpha,4Alpha(S*),5Beta,6Aalpha]]-4-[2-Bromo-5-Cyclohexyl-5-Oxo-3-[(Trimethylsilyl)Oxy]-1-Pentenyl]Hexahydro-2H-Cyclopenta[B]-5-Furyl Benzoate
CAS No.	94135-05-4
Molecular Formula	C30H41BrO5Si
Molecular Weight	589.64 g/mol
Synonyms	Benzoic acid, [3aR-[3aα,4α(S*),5β,6aα]]-4-[2-bromo-5-cyclohexyl-5-oxo-3-[(trimethylsilyl)oxy]-1-penten-1-yl]hexahydro-2H-cyclopenta[b]furan-5-yl ester; (3aR,4R,5S,6aS)-4-[(2E)-2-Bromo-5-cyclohexyl-5-oxo-3-[(trimethylsilyl)oxy]pent-2-en-1-yl]-5-(benzoyloxy)hexahydro-2H-cyclopenta[b]furan; TMS-protected bromo-enone cyclopentafuryl benzoate derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR (1H & 13C), and Mass Spectrometry to confirm identity, purity, and isomeric composition. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support our partners in meeting the stringent data requirements for pharmaceutical regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container for extended periods to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.