Description

(5-Chloro-2-Hydroxy-4-Methylphenyl) (4-Chlorophenyl) Ketone is a specialized organic compound belonging to the diaryl ketone class, serving as a crucial synthetic intermediate in advanced chemical manufacturing. Its molecular structure, featuring chloro and hydroxy substituents, makes it a valuable building block for creating complex molecules with specific electronic and steric properties. This high-purity intermediate is primarily sought by the pharmaceutical and agrochemical industries for research and development, as well as for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to construct complex biaryl systems.
• Dye and Pigment Intermediate: Acts as a precursor for the synthesis of high-performance dyes and pigments due to its ketone backbone and substituents.
• Laboratory Reagent: Utilized in academic and industrial R&D settings for method development and exploratory chemistry.

Basic Information

Product Name	(5-Chloro-2-Hydroxy-4-Methylphenyl) (4-Chlorophenyl) Ketone
CAS No.	94134-54-0
Molecular Formula	C14H10Cl2O2
Molecular Weight	281.14 g/mol
Synonyms	1-(5-Chloro-2-hydroxy-4-methylphenyl)-1-(4-chlorophenyl)methanone; 2-Hydroxy-5-chloro-4-methyl-4'-chlorobenzophenone; 4-Chloro-2-hydroxy-5-methylbenzophenone; (4-Chlorophenyl)(5-chloro-2-hydroxy-4-methylphenyl)methanone; NSC 405124; Benzophenone, 5-chloro-2-hydroxy-4-methyl-4'-chloro-; Ketone, (5-chloro-2-hydroxy-4-methylphenyl) (4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our (5-Chloro-2-Hydroxy-4-Methylphenyl) (4-Chlorophenyl) Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent batch-to-batch quality. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be kept under inert atmosphere for long-term storage to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.