Description

8-Chloromethylquinoline is a versatile and reactive organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in the chloromethyl group, which serves as a key functional handle for further derivatization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides that incorporate the quinoline scaffold for enhanced efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the development of organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Biology Probes: Utilized to create tagged or modified quinoline derivatives for studying biological processes and target engagement.
• Fine Chemical Production: Acts as a critical intermediate for manufacturing dyes, corrosion inhibitors, and other high-value specialty chemicals.

Basic Information

Product Name	8-Chloromethylquinoline
CAS No.	94127-04-5
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	Quinoline, 8-(chloromethyl)-; 8-(Chloromethyl)quinoline; 8-Quinolylmethyl chloride; 1-(Chloromethyl)isoquinoline (common mis-assignment); 8-Chloromethyl-chinolin
EINECS	Contact for details

Quality Control

Our 8-Chloromethylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.