Description

8-Phenyl-1,4-dioxaspiro[4.5]decan-8-ol is a high-value, synthetically versatile spirocyclic compound featuring a protected ketone group and a tertiary alcohol functionality. This unique molecular architecture makes it a critical chiral building block and intermediate for the synthesis of complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), advanced materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug molecules, particularly those requiring spirocyclic or sterically hindered alcohol motifs.
• Asymmetric Synthesis: Used as a building block for constructing enantiomerically pure compounds in medicinal chemistry and catalysis research.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, advanced polymers, and performance materials where its rigid spiro structure imparts specific properties.
• Agrochemical Research: Acts as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Academic & R&D: Utilized in organic chemistry research for methodology development and the study of spirocyclic compound reactivity.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex aroma chemicals with unique olfactory profiles.

Basic Information

Item	Details
Product Name	8-Phenyl-1,4-dioxaspiro[4.5]decan-8-ol
CAS No.	94112-58-0
Molecular Formula	C16H20O3
Molecular Weight	260.33 g/mol
Synonyms	8-Phenyl-1,4-dioxaspiro[4.5]decan-8-ol; 8-Hydroxy-8-phenyl-1,4-dioxaspiro[4.5]decane; 8-Phenyl-8-hydroxy-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decan-8-ol, 8-phenyl-; 8-Phenyl-1,4-dioxaspiro[4,5]decan-8-ol; 8-Phenyl-8-hydroxy-2,3-benzo-1,4-dioxaspiro[4.5]decane (common misnomer); Phenyl spiroketal alcohol intermediate
EINECS	Contact for details

Quality Control

Our 8-Phenyl-1,4-dioxaspiro[4.5]decan-8-ol is produced under strict quality management protocols. We offer material suitable for research and industrial synthesis, with typical purity grades ranging from 95% to 98%+. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.