Description

2,3,3-Trimethylbicyclo[2.2.1]heptane-2-thiol is a specialized bicyclic thiol compound with a unique, rigid molecular structure. This compound matters as a high-value chemical intermediate and chiral building block, prized for its ability to impart specific steric and electronic properties in advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its bicyclic framework contributes to biological activity and stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for asymmetric catalysis.
• Fragrance and Flavor Chemistry: Acts as a building block for synthetic musk compounds and other complex odorants due to its robust, camphor-like skeleton.
• Material Science Research: Investigated as a monomer or additive for specialty polymers to modify thermal and mechanical properties.
• Chemical Derivatization: Utilized to introduce the thiol functional group into complex molecules for further conjugation or labeling.

Basic Information

Product Name	2,3,3-Trimethylbicyclo[2.2.1]heptane-2-thiol
CAS No.	94089-04-0
Molecular Formula	C10H18S
Molecular Weight	170.31 g/mol
Synonyms	2-Thiofenchol; 2,3,3-Trimethyl-2-norbornanethiol; 2-Thioisofenchyl alcohol (deprotonated form); 2-Mercapto-2,3,3-trimethylnorbornane; Bicyclo[2.2.1]heptane-2-thiol, 2,3,3-trimethyl-; Trimethylbicycloheptanethiol; Isobornyl mercaptan (related isomer); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 2,3,3-Trimethylbicyclo[2.2.1]heptane-2-thiol is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including assay by GC or HPLC, enantiomeric purity (if applicable), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.