Description

(1R,2R)-2-Amino-2,3-Dihydro-1H-Inden-1-Ol CAS NO 94077-01-7 is a high-purity chiral amino alcohol building block of significant importance in asymmetric synthesis. This compound serves as a critical intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals, enabling the creation of molecules with specific three-dimensional configurations. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, facilitating enantioselective hydrogenation and carbon-carbon bond formation.
• Agrochemical Synthesis: Building block for creating chiral active ingredients in herbicides, fungicides, and insecticides with improved efficacy and environmental profile.
• Fine Chemical Production: Intermediate in the manufacture of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Process Research: Valuable reagent for methodological development in organic chemistry and scale-up process optimization studies.

Basic Information

Product Name	(1R,2R)-2-Amino-2,3-Dihydro-1H-Inden-1-Ol
CAS No.	94077-01-7
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(1R,2R)-1-Aminoindan-2-ol; (1R,2R)-2-Amino-1-indanol; (1R,2R)-1,2-Dihydro-2-amino-1H-inden-1-ol; (1R,2R)-1,2-Dihydro-1-hydroxy-2-aminoindene; (1R,2R)-trans-1-Amino-2-indanol; (1R,2R)-trans-2-Aminoindan-1-ol; (1R,2R)-Aminoindanol; cis-(1R,2R)-1-Amino-2-indanol
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-Amino-2,3-Dihydro-1H-Inden-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.