Description

2,4-Dinitrophenol-3,5,6-D3 is a deuterium-labeled isotopologue of the classic metabolic uncoupler 2,4-Dinitrophenol (2,4-DNP). This compound matters for its critical role as an internal standard in advanced analytical chemistry, enabling precise quantification and metabolic pathway tracing in complex biological and environmental matrices. It is primarily needed by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors, where high-fidelity mass spectrometry and NMR studies are conducted.

Application

• Internal Standard for Quantitative Analysis: Used as a stable, isotopically labeled reference standard in LC-MS and GC-MS for the accurate quantification of unlabeled 2,4-Dinitrophenol in research and regulatory testing.
• Metabolic and Pharmacokinetic Studies: Serves as a tracer in studies investigating the absorption, distribution, metabolism, and excretion (ADME) of 2,4-DNP and related compounds.
• Environmental Analysis: Employed in method development and validation for detecting trace levels of nitrophenol pollutants in water, soil, and industrial waste samples.
• Biochemical Research: Facilitates mechanistic studies on mitochondrial uncoupling and cellular bioenergetics by providing a distinguishable analog for experimental control.
• Pharmaceutical Impurity Profiling: Acts as a critical tool in the identification and quantification of potential genotoxic impurities and degradation products in drug substances.
• Forensic and Toxicology Testing: Provides a reliable standard for confirmatory testing in forensic analyses involving metabolic uncouplers.

Basic Information

Product Name	2,4-Dinitrophenol-3,5,6-D3
CAS No.	93951-77-0
Molecular Formula	C6HD3N2O5
Molecular Weight	186.11 g/mol
Synonyms	2,4-DNP-d3; 2,4-Dinitrophenol-d3; D3-2,4-Dinitrophenol; [3,5,6-2H3]-2,4-Dinitrophenol; 2,4-Dinitrophenol (phenyl-3,5,6-d3); Deuteronated 2,4-Dinitrophenol; Isotopically Labeled 2,4-DNP; 1-Hydroxy-2,4-dinitrobenzene-3,5,6-d3
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dinitrophenol-3,5,6-D3 is produced and analyzed under strict quality management protocols to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as isotopic purity (Atom % D), chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and incompatible materials such as strong reducing agents and bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.