Description

8-(Trifluoromethyl)Quinolin-4(1H)-One is a high-value trifluoromethyl-substituted quinolinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both the quinolinone core and a trifluoromethyl group, makes it an essential intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Research: Used to develop novel pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science: Building block for creating specialty chemicals, including organic light-emitting diodes (OLEDs) and advanced polymers.
• Chemical Synthesis: Versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Academic & R&D: Fundamental research compound in universities and corporate labs for exploring new heterocyclic chemistry and fluorination effects.

Basic Information

Product Name	8-(Trifluoromethyl)Quinolin-4(1H)-One
CAS No.	93919-57-4
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	4-Hydroxy-8-(trifluoromethyl)quinoline; 8-(Trifluoromethyl)-4-quinolinol; 8-(Trifluoromethyl)-4-hydroxyquinoline; 8-Trifluoromethyl-4(1H)-quinolinone; 8-Trifluoromethyl-4-hydroxyquinoline; 4-Quinolinol, 8-(trifluoromethyl)-; 1H-Quinolin-4-one, 8-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Quinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.