Description

3-Phenylethynyl-Benzoic Acid is a high-purity organic building block featuring a terminal alkyne group attached to a benzoic acid core, making it a versatile intermediate for advanced synthesis. This compound is critical for researchers and manufacturers developing new materials and active pharmaceutical ingredients (APIs) through cross-coupling and click chemistry reactions. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and the production of specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of high-performance polymers, resins, and liquid crystalline materials.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and conductive polymers.
• Chemical Research: A valuable reagent in academic and industrial laboratories for Sonogashira coupling and other metal-catalyzed reactions.
• Bioconjugation: The alkyne moiety allows for use in click chemistry applications for labeling and modifying biomolecules.

Basic Information

Product Name	3-Phenylethynyl-Benzoic Acid
CAS No.	93866-50-3
Molecular Formula	C15H10O2
Molecular Weight	222.24 g/mol
Synonyms	3-(Phenylethynyl)benzoic Acid; m-(Phenylethynyl)benzoic Acid; Benzoic acid, 3-(2-phenylethynyl)-; 3-Ethynylbenzoic Acid Phenyl Derivative; [1,1'-Biphenyl]-3-carboxylic Acid, 4'-Ethynyl- (related); PEBA (abbreviation); m-Carboxyphenylphenylacetylene
EINECS	Contact for details

Quality Control

Our 3-Phenylethynyl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.