Description

L-Prolinium (R)-α-Hydroxybenzeneacetate is a high-purity chiral salt derived from the amino acid L-proline and mandelic acid. This compound is a critical intermediate and building block in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules, particularly for neurological and cardiovascular therapies.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical reactions.
• Resolution Agent: Employed in the chiral resolution of racemic mixtures to isolate single enantiomers with high optical purity.
• Agrochemical Synthesis: Serves as a building block for developing enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and process chemistry R&D.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	L-Prolinium (R)-α-Hydroxybenzeneacetate
CAS No.	93803-22-6
Molecular Formula	C13H17NO4
Molecular Weight	251.28 g/mol
Synonyms	L-Prolinium (R)-Mandelate; (R)-Mandelic Acid L-Prolinium Salt; L-Prolinium (R)-2-Hydroxy-2-phenylacetate; Prolinium (R)-Mandelate; (R)-(-)-Mandelic Acid L-Proline Salt; Proline Mandelate Salt; 93803-22-6; L-Proline (R)-Mandelate Salt
EINECS	Contact for details

Quality Control

Our L-Prolinium (R)-α-Hydroxybenzeneacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.