Description

3-Quinolinecarboxylic Acid, 6-Chloro-4-Hydroxy-2-Phenyl-, Ethyl Ester is a high-purity, synthetically versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring chloro, hydroxy, and phenyl substituents, makes it a valuable intermediate for creating complex molecules with targeted biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the quinoline scaffold is active.
• Agrochemical Research: Used in developing advanced pesticides, herbicides, and fungicides, leveraging its halogenated structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or emissive layer materials in electronic displays.
• Coordination Chemistry & Ligand Synthesis: The functional groups allow for chelation with metal ions, useful in creating catalysts or metal-organic frameworks (MOFs).
• Dye & Pigment Industry: Intermediate for producing specialized quinoline-based dyes with specific light-fastness and color properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for building compound libraries in high-throughput screening.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 6-Chloro-4-Hydroxy-2-Phenyl-, Ethyl Ester
CAS No.	93663-74-2
Molecular Formula	C18H14ClNO3
Molecular Weight	327.76 g/mol
Synonyms	Ethyl 6-Chloro-4-hydroxy-2-phenylquinoline-3-carboxylate; 6-Chloro-4-hydroxy-2-phenylquinoline-3-carboxylic acid ethyl ester; 2-Phenyl-6-chloro-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; Quinoline-3-carboxylic acid, 6-chloro-4-hydroxy-2-phenyl-, ethyl ester; 93663-74-2; 6-Chloro-4-hydroxy-2-phenyl-3-quinolinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-Quinolinecarboxylic Acid, 6-Chloro-4-Hydroxy-2-Phenyl-, Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.