Description

8-Methoxy-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the quinoline carboxylic acid class of compounds. This compound is a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with therapeutic potential in various disease areas. It is essential for research and development chemists, process development scientists, and manufacturers in the global pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of quinolone-based antibiotics and other therapeutic agents.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic frameworks due to its reactive carboxylic acid and ketone functional groups.
• Research & Development (R&D): Serves as a standard or starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies and new molecular entity (NME) discovery.
• Process Chemistry: Employed in the scale-up and optimization of synthetic pathways for the commercial production of target molecules in pilot plants and manufacturing facilities.
• Reference Standard: Can be utilized as an analytical reference standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Methoxy-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid
CAS No.	93445-77-3
Molecular Formula	C12H9NO4
Molecular Weight	231.20 g/mol
Synonyms	8-Methoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid; 1,4-Dihydro-8-methoxy-4-oxoquinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 1,4-dihydro-8-methoxy-4-oxo-; 8-Methoxy-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid; 8-Methoxy-4-oxo-1H-quinoline-2-carboxylic acid; 8-Methoxycarbostyril-2-carboxylic acid; 8-Methoxy-2-carboxy-4(1H)-quinolone
EINECS	Contact for details

Quality Control

Our 8-Methoxy-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.