Description

1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is a high-purity pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of advanced fluoroquinolone antibiotic agents. It is essential for manufacturers and R&D facilities in the pharmaceutical and fine chemical sectors seeking reliable, high-quality raw materials for API production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of third and fourth-generation fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in research and scale-up for novel antibacterial drug candidates.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Reference Standard: Employed as an analytical standard for quality control and regulatory compliance in pharmaceutical manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	93107-30-3
Molecular Formula	C13H9F2NO3
Molecular Weight	265.22 g/mol
Synonyms	6,7-Difluoro-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6,7-Difluoro-1-cyclopropyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Quinolone-3-carboxylic acid derivative; Fluoroquinolone intermediate; CP-67,704 (developmental code); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FTIR and NMR, to ensure it meets stringent specifications for pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.