Description

6-Chloro-6-Defluoro Ciprofloxacin is a key fluorinated quinolone derivative and a crucial advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel antibacterial agents and for research into structure-activity relationships within the quinolone class. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing next-generation antimicrobial therapies and studying bacterial resistance mechanisms.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel fluoroquinolone antibiotics and their analogs.
• Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) to develop new antibacterial agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of specialized quinolone-based active pharmaceutical ingredients (APIs).
• Biochemical Studies: Utilized in microbiological and pharmacological research to investigate mechanisms of action and bacterial resistance.

Basic Information

Product Name	6-Chloro-6-Defluoro Ciprofloxacin
CAS No.	93106-58-2
Molecular Formula	C17H18ClN3O3
Molecular Weight	347.80 g/mol
Synonyms	1-Cyclopropyl-6-chloro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; 6-Chloro-1-cyclopropyl-7-(piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6-Chloro-desfluoro Ciprofloxacin; 6-Chloro-6-defluoro Ciprofloxacin; Ciprofloxacin 6-Chloro-6-defluoro analog; 6-Cl-6-dF Cipro
EINECS	Contact for details

Quality Control

Our 6-Chloro-6-Defluoro Ciprofloxacin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.