Description

(R)-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid CAS NO 92977-00-9 is a high-value, non-proteinogenic chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its enantiopure (R)-configuration makes it indispensable for constructing complex molecules with precise stereochemistry, directly impacting the efficacy and safety of the final products. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides for enhanced biological activity.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Peptidomimetics & Bioactive Molecules: Integral for constructing constrained peptide analogs and other bioactive compounds that mimic natural peptide structures.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D for methodological studies in organic chemistry.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals requiring a tetrahydroquinoline scaffold with a carboxylic acid functionality.

Basic Information

Product Name	(R)-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid
CAS No.	92977-00-9
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydro-2-quinolinecarboxylic acid; (R)-THQCA; (R)-2-Carboxy-1,2,3,4-tetrahydroquinoline; (R)-1,2,3,4-Tetrahydroquinoline-2-carboxylic acid; (2R)-1,2,3,4-Tetrahydroquinoline-2-carboxylic acid; (R)-Tic-OH; (R)-2-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our production of (R)-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.