Description

4,7-Methano-1H-Indole-2-Carboxylicacid,Octahydro-,[2S-(2-α-,3A-α-,4-Bta-,7-Bta-,7A-α-)]-(9Ci) is a complex, stereochemically defined indole derivative that serves as a critical chiral building block in advanced organic synthesis. This compound matters for its rigid, polycyclic framework, which is instrumental in constructing molecules with precise three-dimensional architectures, a key requirement in modern pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing new generation pesticides and herbicides with enhanced specificity and lower environmental impact.
• Asymmetric Catalysis Ligand Precursor: Its complex structure can be modified to create novel chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Natural Product Synthesis: Acts as a core fragment in the total synthesis of complex indole alkaloids and other natural products for biological evaluation.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers with unique optical or electronic properties.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4,7-Methano-1H-Indole-2-Carboxylicacid,Octahydro-,[2S-(2-α-,3A-α-,4-Bta-,7-Bta-,7A-α-)]-(9Ci)
CAS No.	92842-22-3
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(2S,3aS,4R,7R,7aS)-Octahydro-4,7-methano-1H-indole-2-carboxylic acid; (2S,3aS,4R,7R,7aS)-Octahydro-4,7-methanoindole-2-carboxylic acid; (2S,3aS,4R,7R,7aS)-Octahydro-4,7-methano-2H-isoindole-2-carboxylic acid; 4,7-Methano-1H-indole-2-carboxylic acid, octahydro-, (2S,3aS,4R,7R,7aS)-; 92842-22-3; Octahydro-4,7-methano-1H-indole-2-carboxylic acid, (2S,3aS,4R,7R,7aS)-; (2S,3aS,4R,7R,7aS)-2-Carboxyhexahydro-4,7-methanoindole
EINECS	Contact for details

Quality Control

Our production of 4,7-Methano-1H-Indole-2-Carboxylicacid,Octahydro-,[2S-(2-α-,3A-α-,4-Bta-,7-Bta-,7A-α-)]-(9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided and can be tailored to meet customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.