Description

(1H-Benzimidazol-2-Ylmethyl)Methylamine Dihydrochloride is a high-purity, versatile benzimidazole derivative primarily used as a critical building block in pharmaceutical research and development. Its significance lies in its role as a key synthetic intermediate for creating novel therapeutic agents, particularly in the areas of kinase inhibitors and other small-molecule drugs. This compound is essential for medicinal chemists and R&D departments in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Serves as a precursor for developing probes and inhibitors used in biological pathway analysis and target validation.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for advanced material science and agrochemical research.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for proprietary research programs and custom synthesis projects.

Basic Information

Product Name	(1H-Benzimidazol-2-Ylmethyl)Methylamine Dihydrochloride
CAS No.	92809-96-6
Molecular Formula	C9H12N3·2HCl
Molecular Weight	239.13 g/mol (as free base: 162.21)
Synonyms	2-(Aminomethyl)-1H-benzimidazole Dihydrochloride; N-Methyl-1H-benzimidazol-2-ylmethanamine Dihydrochloride; 1H-Benzimidazole-2-methanamine, N-methyl-, Dihydrochloride; (Benzimidazol-2-ylmethyl)methylamine Dihydrochloride; 2-(Methylaminomethyl)benzimidazole Dihydrochloride; N-Methyl-2-benzimidazolemethanamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (1H-Benzimidazol-2-Ylmethyl)Methylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.