Description

Sialylfucosyllactosaminoglycan CAS NO 92767-35-6 is a complex oligosaccharide, specifically a sialylated and fucosylated derivative of lactosaminoglycan. This compound is of significant interest in biochemical and biomedical research due to its role as a specific ligand for selectins, which are involved in cell adhesion and inflammatory processes. It is primarily utilized by research institutions and pharmaceutical companies engaged in glycobiology, immunology, and the development of novel therapeutic agents targeting inflammation and metastasis.

Application

• Glycobiology Research: Used as a standard or substrate to study glycosylation patterns, enzyme activities (sialyltransferases, fucosyltransferases), and carbohydrate-protein interactions.
• Immunology & Inflammation Studies: Serves as a key ligand for E-selectin and P-selectin binding assays to investigate leukocyte rolling, adhesion, and the molecular mechanisms of inflammatory diseases.
• Drug Discovery & Development: Employed in high-throughput screening and validation of potential anti-inflammatory or anti-metastatic drugs that target selectin-mediated pathways.
• Diagnostic Reagent Development: Can be used in the development of diagnostic kits or biosensors for detecting specific cellular adhesion events or disease biomarkers.
• Biomaterial Functionalization: Applied to coat surfaces or nanoparticles to create bioactive materials that mimic cell surface interactions for tissue engineering or targeted delivery applications.

Basic Information

Product Name	Sialylfucosyllactosaminoglycan
CAS No.	92767-35-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sialyl Lewis X; Sialyl Lex; SLex; Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAc; CD15s; 3'-Sialyl-N-acetyllactosamine Fucoside; Sialylfucosyllactosamine; 3'-Sialyllacto-N-fucopentaose III
EINECS	Contact for details

Quality Control

Our Sialylfucosyllactosaminoglycan is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR and mass spectrometry to confirm structure and identity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity (Binding Assay)	Active

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.