Description

(5R,6R)-5,6-Dihydro-7,12-Dimethylbenz[A]Anthracene-5,6-Diol is a high-purity, stereospecific dihydrodiol derivative of a polycyclic aromatic hydrocarbon (PAH). This compound is of significant value as a key reference standard and synthetic intermediate in advanced chemical research and development. It is primarily required by pharmaceutical, biotechnology, and academic research institutions for studies in toxicology, metabolic pathway analysis, and the synthesis of more complex molecular entities.

Application

• Biochemical Research: Used as a critical metabolite standard in studies investigating the metabolic activation and detoxification pathways of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology & Carcinogenesis Studies: Serves as a precise analytical standard for quantifying DNA adduct formation and understanding the mechanisms of PAH-induced genotoxicity.
• Pharmaceutical Intermediate: Acts as a chiral building block in the synthesis of more complex molecules for drug discovery programs targeting specific biological pathways.
• Analytical Chemistry: Employed as a high-purity calibrant in HPLC, GC-MS, and other chromatographic methods for method development and validation in environmental and biological monitoring.
• Academic Research: Provides a well-defined compound for fundamental studies in organic chemistry, stereochemistry, and enzymatic dihydroxylation reactions.

Basic Information

Product Name	(5R,6R)-5,6-Dihydro-7,12-Dimethylbenz[A]Anthracene-5,6-Diol
CAS No.	92693-65-7
Molecular Formula	C₂₀H₁₈O₂
Molecular Weight	290.36 g/mol
Synonyms	(5R,6R)-7,12-Dimethylbenz[a]anthracene-5,6-diol; (5R,6R)-Dihydro-7,12-dimethylbenz[a]anthracene-5,6-diol; (5R,6R)-5,6-Dihydroxy-5,6-dihydro-7,12-dimethylbenz[a]anthracene; (5R,6R)-DMBA-5,6-diol; (+)-(5R,6R)-Dihydro-7,12-dimethylbenz[a]anthracene-5,6-diol; 7,12-DMBA-5,6-diol (stereospecific); 5,6-Dihydro-7,12-dimethylbenz[a]anthracene-5,6-diol (R,R-isomer)
EINECS	Contact for details

Quality Control

Our (5R,6R)-5,6-Dihydro-7,12-Dimethylbenz[A]Anthracene-5,6-Diol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. All products undergo rigorous analytical testing, including HPLC for purity and chiral integrity and spectroscopic confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the container under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. This material is light-sensitive and easily oxidized.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (5R,6R isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.