Description

9-Oxo-1,9-Dihydro-Pyrazolo[5,1-B]Quinazoline-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of new drug candidates, especially for oncology and central nervous system (CNS) targets.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex polycyclic nitrogen-containing heterocycles due to its reactive aldehyde and quinazoline moieties.
• Agrochemical Research: Potential application as a scaffold for developing novel herbicides or pesticides with specific modes of action.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials or specialty dyes requiring fused heteroaromatic systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	9-Oxo-1,9-Dihydro-Pyrazolo[5,1-B]Quinazoline-3-Carbaldehyde
CAS No.	92560-76-4
Molecular Formula	C12H7N3O2
Molecular Weight	225.20 g/mol
Synonyms	Pyrazolo[5,1-b]quinazoline-3-carboxaldehyde, 1,9-dihydro-9-oxo-; 9-Oxo-1,9-dihydropyrazolo[5,1-b]quinazoline-3-carbaldehyde; 1,9-Dihydro-9-oxopyrazolo[5,1-b]quinazoline-3-carboxaldehyde; 92560-76-4; Pyrazoloquinazoline carbaldehyde; 3-Formyl-9-oxo-1,9-dihydropyrazolo[5,1-b]quinazoline
EINECS	Contact for details

Quality Control

Our 9-Oxo-1,9-Dihydro-Pyrazolo[5,1-B]Quinazoline-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades, including research and cGMP grades, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.