Description

6-Chloroquinoline-2,3-Dicarboxylic Acid Diethyl Ester is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its functionalized quinoline core, which serves as a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, antimalarials, and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing advanced crop protection agents, such as herbicides and fungicides with specific modes of action.
• Material Science Research: Used in the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its conjugated structure and coordination sites.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Potential starting material for synthesizing specialized quinoline-derived dyes and colorants.
• Ligand Synthesis: Useful for creating chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	6-Chloroquinoline-2,3-Dicarboxylic Acid Diethyl Ester
CAS No.	92525-74-1
Molecular Formula	C₁₆H₁₆ClNO₄
Molecular Weight	321.76 g/mol
Synonyms	Diethyl 6-Chloroquinoline-2,3-dicarboxylate; 6-Chloro-2,3-quinolinedicarboxylic Acid Diethyl Ester; 6-Chloroquinoline-2,3-dicarboxylic Acid Diethyl Ester; Ethyl 6-Chloro-2,3-quinolinedicarboxylate; 2,3-Di(ethoxycarbonyl)-6-chloroquinoline; 6-Chloro-2,3-bis(ethoxycarbonyl)quinoline; Quinoline-2,3-dicarboxylic acid, 6-chloro-, diethyl ester
EINECS	Contact for details

Quality Control

Our 6-Chloroquinoline-2,3-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.